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InnateDB Protein
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IDBP-92239.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CUZD1
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Protein Name
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CUB and zona pellucida-like domains 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000357896
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InnateDB Gene
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IDBG-92233 (CUZD1)
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Protein Structure
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| Function |
CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes. May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. {ECO:0000250UniProtKB:P70412, ECO:0000269PubMed:15184879}.
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| Subcellular Localization |
Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Associated with zymogen granule membranes. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Detected in pancreas and epithelium of ovary. Expressed at higher levels in ovarian tumors than in normal tissue. {ECO:0000269PubMed:15184879}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| PDB ID |
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q86UP6
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
50624
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| UniGene |
Hs.647182
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| RefSeq |
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| HUGO |
HGNC:17937
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| OMIM |
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| CCDS |
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| HPRD |
06476
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4