Version 5.4
Homo sapiens Protein: MB21D1
Summary
InnateDB Protein IDBP-92360.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MB21D1
Protein Name Mab-21 domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359342
InnateDB Gene IDBG-92358 (MB21D1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0046872 metal ion binding
GO:0061501 cyclic-GMP-AMP synthase activity
Biological Process
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0009190 cyclic nucleotide biosynthetic process
GO:0032481 positive regulation of type I interferon production
GO:0045087 innate immune response (InnateDB)
GO:0051607 defense response to virus
GO:0071360 cellular response to exogenous dsRNA
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR024810 Mab-21 domain
PFAM PF03281
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N884
PhosphoSite PhosphoSite-Q8N884
TrEMBL
UniProt Splice Variant
Entrez Gene 115004
UniGene Hs.658405
RefSeq
HUGO HGNC:21367
OMIM 613973
CCDS
HPRD 12857
IMGT
EMBL AC019205 AK097148 AL603910 BC012928 BC108714 BC113606 BC113608 BC143694 KC294566
GenPept AAH12928 AAI08715 AAI13607 AAI13609 AAI43695 AGB51853 BAC04965 CAI14878 CAI14879

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca