Homo sapiens Protein: SPSB3
Summary
InnateDB Protein IDBP-9292.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPSB3
Protein Name splA/ryanodine receptor domain and SOCS box containing 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301717
InnateDB Gene IDBG-9290 (SPSB3)
Protein Structure
UniProt Annotation
Function May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001496 SOCS protein, C-terminal
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF07525
PF00622
PRINTS
PIRSF
SMART SM00253
SM00969
SM00449
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PJ21
PhosphoSite PhosphoSite-Q6PJ21
TrEMBL H3BP12
UniProt Splice Variant
Entrez Gene 90864
UniGene Hs.592080
RefSeq
HUGO HGNC:30629
OMIM 611659
CCDS CCDS32365
HPRD 18107
IMGT
EMBL AC012180 AE006639 AF403028 BC007588 BC024244 BC041897 BC047441 CH471112
GenPept AAH07588 AAH24244 AAH41897 AAH47441 AAK61293 AAL57347 EAW85619 EAW85620 EAW85622 EAW85623