Version 5.4
Homo sapiens Protein: NPDC1
Summary
InnateDB Protein IDBP-93016.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPDC1
Protein Name neural proliferation, differentiation and control, 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360660
InnateDB Gene IDBG-93014 (NPDC1)
Protein Structure
UniProt Annotation
Function Suppresses oncogenic transformation in neural and non- neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR009635 Neural proliferation differentiation control-1
PFAM PF06809
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQX5
PhosphoSite PhosphoSite-Q9NQX5
TrEMBL
UniProt Splice Variant
Entrez Gene 56654
UniGene Hs.719906
RefSeq NP_056207
HUGO HGNC:7899
OMIM 605798
CCDS CCDS7024
HPRD 12048
IMGT
EMBL AF272357 AF283247 AF285836 AL050221 AL807752 BC004217
GenPept AAF76225 AAF82603 AAH04217 AAK27328 CAB43321 CAI12775

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca