InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAP1GAP

Summary

InnateDB Protein

IDBP-93275.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAP1GAP

Protein Name

RAP1 GTPase activating protein

Synonyms

RAP1GA1; RAP1GAP1; RAP1GAPII; RAPGAP;

Species

Homo sapiens

Ensembl Protein

ENSP00000363893

InnateDB Gene

IDBG-93263 (RAP1GAP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	24 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005096	GTPase activator activity
GO:0005515	protein binding
GO:0017016	Ras GTPase binding
GO:0030695	GTPase regulator activity
GO:0042803	protein homodimerization activity
GO:0046582	Rap GTPase activator activity

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0032318	regulation of Ras GTPase activity
GO:0032854	positive regulation of Rap GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0050790	regulation of catalytic activity
GO:0051056	regulation of small GTPase mediated signal transduction