InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IRAK1BP1

Summary

InnateDB Protein

IDBP-93347.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IRAK1BP1

Protein Name

interleukin-1 receptor-associated kinase 1 binding protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000358956

InnateDB Gene

IDBG-93345 (IRAK1BP1)

Protein Structure

UniProt Annotation

Function

Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007249	I-kappaB kinase/NF-kappaB signaling
GO:0045087	innate immune response (InnateDB)