Version 5.4
Homo sapiens Protein: ABLIM2
Summary
InnateDB Protein IDBP-9363.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABLIM2
Protein Name actin binding LIM protein family, member 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000317020
InnateDB Gene IDBG-9357 (ABLIM2)
Protein Structure
UniProt Annotation
Function May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. {ECO:0000269PubMed:17194709}.
Subcellular Localization Cytoplasm. Note=In skeletal muscle, sarcomeric or cosarcomeric localization. {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in skeletal muscle. {ECO:0000269PubMed:17194709}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008270 zinc ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007010 cytoskeleton organization
GO:0007411 axon guidance
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
IPR003128 Villin headpiece
PFAM PF00412
PF02209
PRINTS
PIRSF
SMART SM00132
SM00153
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6H8Q1
PhosphoSite PhosphoSite-Q6H8Q1
TrEMBL Q4W5G4
UniProt Splice Variant
Entrez Gene 84448
UniGene Hs.233404
RefSeq XP_005248076
HUGO HGNC:19195
OMIM 612544
CCDS
HPRD
IMGT
EMBL AB058711 AC097381 AC104650 AC114807 AJ748600 AJ748601 AK094754 AK094798 AL834195 BC067214 BC122567 DQ413177
GenPept AAH67214 AAI22568 AAY40931 ABD83330 BAB47437 BAC04414 BAC04427 CAD38885 CAG38375 CAG38376

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca