Version 5.4
Homo sapiens Protein: UBE2CBP
Summary
InnateDB Protein IDBP-93710.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2CBP
Protein Name ubiquitin-conjugating enzyme E2C binding protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358762
InnateDB Gene IDBG-93704 (UBE2CBP)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. {ECO:0000269PubMed:15749827}.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR019193 Ubiquitin-conjugating enzyme E2-binding protein
PFAM PF09814
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z6J8
PhosphoSite PhosphoSite-Q7Z6J8
TrEMBL D6RHY9
UniProt Splice Variant
Entrez Gene 90025
UniGene Hs.565422
RefSeq NP_944602
HUGO HGNC:21381
OMIM 612495
CCDS CCDS34491
HPRD 12861
IMGT
EMBL AB126062 AK298205 AL034377 AL137544 AL139333 AL355613 AL357121 AL450483 BC053645 BC071763 BC101512 BC101538 CH471051
GenPept AAH53645 AAH71763 AAI01513 AAI01539 BAD01604 BAG60475 CAB70802 CAI13740 CAI15282 CAM28304 EAW48681

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca