InnateDB Protein
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IDBP-93732.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FUOM
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Protein Name
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chromosome 10 open reading frame 125
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000278025
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InnateDB Gene
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IDBG-93730 (FUOM)
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Protein Structure
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Function |
Involved in the interconversion between alpha- and beta- L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O- glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. {ECO:0000269PubMed:17602138}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007721
D-ribose pyranase RbsD/L-fucose mutarotase FucU
IPR023750
RbsD-like domain
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PFAM |
PF05025
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A2VDF0
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PhosphoSite |
PhosphoSite-A2VDF0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
282969
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UniGene |
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RefSeq |
NP_940874
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HUGO |
HGNC:24733
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OMIM |
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CCDS |
CCDS7680
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HPRD |
12564
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IMGT |
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EMBL |
AI333356
AK129527
AL360181
BC129818
BC129819
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GenPept |
AAI29819
AAI29820
BAC85178
CAH70284
CAH70285
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