Version 5.4
Homo sapiens Protein: ZNF436
Summary
InnateDB Protein IDBP-93876.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF436
Protein Name zinc finger protein 436
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000313582
InnateDB Gene IDBG-93874 (ZNF436)
Protein Structure
UniProt Annotation
Function May be a transcriptional repressor. {ECO:0000269PubMed:17089209}.
Subcellular Localization Nucleus {ECO:0000269PubMed:17089209}.
Disease Associations
Tissue Specificity Expressed in fetal brain, heart, liver, spleen, bladder, lung, skin, skeletal muscle, stomach and pancreas. {ECO:0000269PubMed:17089209}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9C0F3
PhosphoSite PhosphoSite-Q9C0F3
TrEMBL Q15921
UniProt Splice Variant
Entrez Gene 80818
UniGene Hs.596438
RefSeq NP_001070663
HUGO HGNC:20814
OMIM 611703
CCDS CCDS233
HPRD 15793
IMGT
EMBL AB051497 AL109936 AL834485 BC056400 CH471134 M88359
GenPept AAA61317 AAH56400 BAB21801 CAD39143 CAI19029 EAW95043 EAW95044

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca