Version 5.4
Homo sapiens Protein: PAQR7
Summary
InnateDB Protein IDBP-94420.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAQR7
Protein Name progestin and adipoQ receptor family member VII
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000363414
InnateDB Gene IDBG-94418 (PAQR7)
Protein Structure
UniProt Annotation
Function Steroid membrane receptor. Binds progesterone in vitro. May be involved in oocyte maturation. {ECO:0000269PubMed:12601167}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder. {ECO:0000269PubMed:12601167, ECO:0000269PubMed:16044242}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
Biological Process
GO:0007275 multicellular organismal development
GO:0043401 steroid hormone mediated signaling pathway
GO:0048477 oogenesis
GO:0048545 response to steroid hormone
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004254 Hly-III-related
PFAM PF03006
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86WK9
PhosphoSite PhosphoSite-Q86WK9
TrEMBL
UniProt Splice Variant
Entrez Gene 164091
UniGene Hs.602009
RefSeq NP_848509
HUGO HGNC:23146
OMIM 607779
CCDS CCDS267
HPRD 09692
IMGT
EMBL AF313620 AL033528 AY424285 BC034015 BC042298 CH471059
GenPept AAH34015 AAO47233 AAR08373 CAM12867 EAX07862

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca