Version 5.4
Homo sapiens Protein: EXTL1
Summary
InnateDB Protein IDBP-94457.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXTL1
Protein Name exostoses (multiple)-like 1
Synonyms EXTL;
Species Homo sapiens
Ensembl Protein ENSP00000363398
InnateDB Gene IDBG-94455 (EXTL1)
Protein Structure
UniProt Annotation
Function Probable glycosyltransferase. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016758 transferase activity, transferring hexosyl groups
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
Biological Process
GO:0001501 skeletal system development
GO:0006486 protein glycosylation
Cellular Component
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR004263 Exostosin-like
IPR015338 EXTL2, alpha-1,4-N-acetylhexosaminyltransferase
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF03016
PF09258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92935
PhosphoSite PhosphoSite-Q92935
TrEMBL
UniProt Splice Variant
Entrez Gene 2134
UniGene Hs.150956
RefSeq NP_004446
HUGO HGNC:3515
OMIM 601738
CCDS CCDS271
HPRD 03441
IMGT
EMBL AF083623 AF083624 AF083625 AF083626 AF083627 AF083628 AF083629 AF083630 AF083631 AF083632 AF083633 AF151391 AF153980 AL391650 BC065528 U67191
GenPept AAC51141 AAD02840 AAF73172 AAH65528 CAI17130

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca