Version 5.4
Homo sapiens Protein: SERINC4
Summary
InnateDB Protein IDBP-9477.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERINC4
Protein Name serine incorporator 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000319796
InnateDB Gene IDBG-9475 (SERINC4)
Protein Structure
UniProt Annotation
Function Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. {ECO:0000269PubMed:16120614}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR005016 Serine incorporator/TMS membrane protein
PFAM PF03348
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NH21
PhosphoSite PhosphoSite-A6NH21
TrEMBL
UniProt Splice Variant
Entrez Gene 619189
UniGene Hs.604985
RefSeq NP_001244961
HUGO HGNC:32237
OMIM 614550
CCDS CCDS58360
HPRD
IMGT
EMBL AC018512 BC136669 CH471082 DQ103711
GenPept AAI36670 AAZ80298 EAW77244 EAW77245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca