InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WDTC1

Summary

InnateDB Protein

IDBP-94820.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WDTC1

Protein Name

WD and tetratricopeptide repeats 1

Synonyms

ADP; DCAF9;

Species

Homo sapiens

Ensembl Protein

ENSP00000317971

InnateDB Gene

IDBG-94818 (WDTC1)

Protein Structure

UniProt Annotation

Function

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269PubMed:16964240}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004857	enzyme inhibitor activity
GO:0005515	protein binding
GO:0042393	histone binding
GO:0042826	histone deacetylase binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0006006	glucose metabolic process
GO:0008361	regulation of cell size
GO:0016567	protein ubiquitination
GO:0032869	cellular response to insulin stimulus
GO:0035264	multicellular organism growth
GO:0043086	negative regulation of catalytic activity
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0055082	cellular chemical homeostasis