Version 5.4
Homo sapiens Protein: WDTC1
Summary
InnateDB Protein IDBP-94822.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDTC1
Protein Name WD and tetratricopeptide repeats 1
Synonyms ADP; DCAF9;
Species Homo sapiens
Ensembl Protein ENSP00000355317
InnateDB Gene IDBG-94818 (WDTC1)
Protein Structure
UniProt Annotation
Function May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269PubMed:16964240}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR013026 Tetratricopeptide repeat-containing domain
IPR017986 WD40-repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF00400
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00320
SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N5D0
PhosphoSite PhosphoSite-Q8N5D0
TrEMBL H0YEI6
UniProt Splice Variant
Entrez Gene 23038
UniGene Hs.595963
RefSeq NP_055838
HUGO HGNC:29175
OMIM
CCDS CCDS296
HPRD 10307
IMGT
EMBL AB028960 AK001734 AL590640 AL663123 BC032523 CH471059 FO393419
GenPept AAH32523 BAA82989 BAA91868 EAX07770 EAX07771

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca