Homo sapiens Protein: RTN4IP1
Summary
InnateDB Protein IDBP-94891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RTN4IP1
Protein Name reticulon 4 interacting protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358059
InnateDB Gene IDBG-94889 (RTN4IP1)
Protein Structure
UniProt Annotation
Function Appears to be a potent inhibitor of regeneration following spinal cord injury.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:12067236}.
Disease Associations
Tissue Specificity Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta. {ECO:0000269PubMed:12067236}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR011032 GroES (chaperonin 10)-like
IPR013149 Alcohol dehydrogenase, C-terminal
IPR013154 Alcohol dehydrogenase GroES-like
IPR020843 Polyketide synthase, enoylreductase
PFAM PF00107
PF08240
PRINTS
PIRSF
SMART SM00829
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WWV3
PhosphoSite PhosphoSite-Q8WWV3
TrEMBL B2R9Y1
UniProt Splice Variant
Entrez Gene 84816
UniGene Hs.619148
RefSeq NP_116119
HUGO HGNC:18647
OMIM 610502
CCDS CCDS5056
HPRD 18008
IMGT
EMBL AF439711 AK095207 AK313962 AL390074 AY063761 BC006399
GenPept AAH06399 AAL34525 AAL40856 BAC04499 BAG36678 CAH72095