Version 5.4
Homo sapiens Protein: TXLNA
Summary
InnateDB Protein IDBP-95598.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TXLNA
Protein Name taxilin alpha
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362711
InnateDB Gene IDBG-95594 (TXLNA)
Protein Structure
UniProt Annotation
Function May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous, with much higher expression in heart, kidney, liver and pancreas. {ECO:0000269PubMed:12558796}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005515 protein binding
GO:0019905 syntaxin binding
GO:0030372 high molecular weight B cell growth factor receptor binding
Biological Process
GO:0006887 exocytosis
GO:0008283 cell proliferation
GO:0042113 B cell activation
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR026183 Taxilin family
PFAM PF09728
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40222
PhosphoSite PhosphoSite-P40222
TrEMBL
UniProt Splice Variant
Entrez Gene 200081
UniGene Hs.652501
RefSeq XP_005270651
HUGO HGNC:30685
OMIM 608676
CCDS CCDS353
HPRD 09408
IMGT
EMBL AF516206 AL049795 AL832338 AL832636 AL832637 BC029686 BC046565 BC080578 BC103823 BC103824 CH471059 L15344
GenPept AAH29686 AAH46565 AAH80578 AAI03824 AAI03825 AAO42465 CAD89951 CAD89952 CAD91138 CAI22055 EAX07565 EAX07566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca