Version 5.4
Homo sapiens Protein: VGLL2
Summary
InnateDB Protein IDBP-95779.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VGLL2
Protein Name vestigial like 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000320957
InnateDB Gene IDBG-95775 (VGLL2)
Protein Structure
UniProt Annotation
Function May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Skeletal muscle. {ECO:0000269PubMed:12617818}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007519 skeletal muscle tissue development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR011520 Vestigial/tondu
PFAM PF07545
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N8G2
PhosphoSite PhosphoSite-Q8N8G2
TrEMBL
UniProt Splice Variant
Entrez Gene 245806
UniGene Hs.99324
RefSeq NP_872586
HUGO HGNC:20232
OMIM 609979
CCDS CCDS5115
HPRD 18282
IMGT
EMBL AJ578053 AK096878 AY056583 BC069316 BC100798 BC100799 BC118545 BC118622 CH471051 Z98880
GenPept AAH69316 AAI00799 AAI00800 AAI18546 AAI18623 AAL17720 BAC04881 CAE17331 CAI42376 EAW48211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca