Version 5.4
Homo sapiens Protein: S100PBP
Summary
InnateDB Protein IDBP-95814.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100PBP
Protein Name S100P binding protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362575
InnateDB Gene IDBG-95812 (S100PBP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000269PubMed:15632002}. Note=Colocalizes with S100P in the nucleus. {ECO:0000269PubMed:15632002}.
Disease Associations
Tissue Specificity Expressed in brain, spleen, and lung. Not detected in pancreas or liver. In pancreas, expressed predominantly in islet cells and to a lesser extent in acinar cells, but not expressed in ductal cells. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Detected in pancreatic ductal adenocarcinoma cells (at protein level). Not detected in non-neoplastic ductal epithelium (at protein level). {ECO:0000269PubMed:15632002, ECO:0000269PubMed:18089492}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0048306 calcium-dependent protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96BU1
PhosphoSite PhosphoSite-Q96BU1
TrEMBL E9PSA0
UniProt Splice Variant
Entrez Gene 64766
UniGene Hs.734633
RefSeq NP_001243050
HUGO HGNC:25768
OMIM 611889
CCDS CCDS30666
HPRD 07803
IMGT
EMBL AC114493 AK022965 AK090711 BC015175 BX647667 CH471059
GenPept AAH15175 BAB14335 BAG52216 CAI46038 EAX07503 EAX07504 EAX07505

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca