InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FABP7

Summary

InnateDB Protein

IDBP-96030.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FABP7

Protein Name

fatty acid binding protein 7, brain

Synonyms

B-FABP; BLBP; FABPB; LTR2-FABP7; MRG;

Species

Homo sapiens

Ensembl Protein

ENSP00000357429

InnateDB Gene

IDBG-96028 (FABP7)

Protein Structure

UniProt Annotation

Function

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Expressed in brain and other neural tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0008289	lipid binding

Biological Process

GO:0001964	startle response
GO:0006810	transport
GO:0007399	nervous system development
GO:0008285	negative regulation of cell proliferation
GO:0021846	cell proliferation in forebrain
GO:0022008	neurogenesis
GO:0050673	epithelial cell proliferation
GO:0060134	prepulse inhibition