InnateDB Protein
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IDBP-9646.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FAM109B
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Protein Name
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family with sequence similarity 109, member B
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000312753
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InnateDB Gene
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IDBG-9644 (FAM109B)
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Protein Structure
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Function |
Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. {ECO:0000269PubMed:21233288}.
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Subcellular Localization |
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001849
Pleckstrin homology domain
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PFAM |
PF00169
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PRINTS |
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PIRSF |
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SMART |
SM00233
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TIGRFAMs |
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Modification |
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SwissProt |
Q6ICB4
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PhosphoSite |
PhosphoSite-Q6ICB4
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TrEMBL |
B1AHR3
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UniProt Splice Variant |
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Entrez Gene |
150368
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UniGene |
Hs.368312
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RefSeq |
NP_001002034
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HUGO |
HGNC:27161
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OMIM |
614240
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CCDS |
CCDS33655
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HPRD |
17305
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IMGT |
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EMBL |
BC029776
BC104175
BC104176
CR456454
Z82192
Z99716
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GenPept |
AAH29776
AAI04176
AAI04177
CAG30340
CAI19712
CAI41696
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