Version 5.4
Homo sapiens Protein: FHL3
Summary
InnateDB Protein IDBP-96557.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FHL3
Protein Name four and a half LIM domains 3
Synonyms SLIM2;
Species Homo sapiens
Ensembl Protein ENSP00000362107
InnateDB Gene IDBG-96555 (FHL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Expressed only in skeletal muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 46 [view]
Protein-Protein 45 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007517 muscle organ development
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0030018 Z disc
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
PFAM PF00412
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13643
PhosphoSite PhosphoSite-Q13643
TrEMBL Q96C98
UniProt Splice Variant
Entrez Gene 2275
UniGene Hs.57687
RefSeq NP_004459
HUGO HGNC:3704
OMIM 602790
CCDS CCDS30678
HPRD 09101
IMGT
EMBL AK290641 AL603790 BC001351 BC011697 BC014501 BT007052 CH471059 CR457425 U60116
GenPept AAC04466 AAH01351 AAH11697 AAH14501 AAP35701 BAF83330 CAG33706 CAH69931 EAX07301 EAX07302

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca