InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MOXD1

Summary

InnateDB Protein

IDBP-96638.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MOXD1

Protein Name

monooxygenase, DBH-like 1

Synonyms

dJ248E1.1; MOX; PRO5780;

Species

Homo sapiens

Ensembl Protein

ENSP00000336998

InnateDB Gene

IDBG-96634 (MOXD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in lung, kidney, brain and spinal cord. {ECO:0000269PubMed:15337741, ECO:0000269PubMed:9751809}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004497	monooxygenase activity
GO:0005507	copper ion binding
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000323 Copper type II, ascorbate-dependent monooxygenase, N-terminal
IPR000945 Dopamine beta-hydroxylase-related
IPR005018 DOMON domain
IPR008977 PHM/PNGase F domain

PFAM

PF01082
PF03351

PRINTS

PR00767

PIRSF

SMART

SM00664

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt