InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HBS1L

Summary

InnateDB Protein

IDBP-96828.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HBS1L

Protein Name

HBS1-like (S. cerevisiae)

Synonyms

EF-1a; eRF3c; ERFS; HBS1; HSPC276;

Species

Homo sapiens

Ensembl Protein

ENSP00000356800

InnateDB Gene

IDBG-96822 (HBS1L)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Detected in heart, brain, placenta, liver, muscle, kidney and pancreas. {ECO:0000269PubMed:9872408}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003746	translation elongation factor activity
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006412	translation
GO:0006414	translational elongation
GO:0007165	signal transduction

Cellular Component

GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
IPR004161 Translation elongation factor EFTu/EF1A, domain 2
IPR009000 Translation protein, beta-barrel domain
IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
IPR015033 HBS1-like protein, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF03143
PF03144
PF08938

PRINTS

PR00315

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y450