InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: OLIG3

Summary

InnateDB Protein

IDBP-97030.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OLIG3

Protein Name

oligodendrocyte transcription factor 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000356708

InnateDB Gene

IDBG-97028 (OLIG3)

Protein Structure

UniProt Annotation

Function

May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001106	RNA polymerase II transcription corepressor activity
GO:0003677	DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0010468	regulation of gene expression
GO:0021520	spinal cord motor neuron cell fate specification
GO:0021522	spinal cord motor neuron differentiation
GO:0097476	spinal cord motor neuron migration