Version 5.4
Homo sapiens Protein: KIAA1244
Summary
InnateDB Protein IDBP-97043.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIAA1244
Protein Name KIAA1244
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000251691
InnateDB Gene IDBG-97039 (KIAA1244)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005488 binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
GO:0016192 vesicle-mediated transport
GO:0032012 regulation of ARF protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005802 trans-Golgi network
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000904 Sec7 domain
IPR015403 Domain of unknown function DUF1981, Sec7 associated
IPR016024 Armadillo-type fold
PFAM PF01369
PF09324
PRINTS
PIRSF
SMART SM00222
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5TH69
PhosphoSite PhosphoSite-Q5TH69
TrEMBL C5NM88
UniProt Splice Variant
Entrez Gene 57221
UniGene Hs.623564
RefSeq NP_065073
HUGO HGNC:21213
OMIM
CCDS CCDS5189
HPRD 13845
IMGT
EMBL AB033070 AB252196 AF413080 AL031003 AL031433 AL391240 BC014227 BC033191 BC137174
GenPept AAH14227 AAH33191 AAI37175 AAL04174 BAA86558 BAH83562 CAI19661 CAM28242 CAM28244

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca