Version 5.4
| Homo sapiens Protein: GUCA2A | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-97175.5 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | GUCA2A | ||||||
| Protein Name | guanylate cyclase activator 2A (guanylin) | ||||||
| Synonyms | GCAP-I; GUCA2; STARA; | ||||||
| Species | Homo sapiens | ||||||
| Ensembl Protein | ENSP00000349493 | ||||||
| InnateDB Gene | IDBG-97173 (GUCA2A) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. | ||||||
| Subcellular Localization | Secreted. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Highly expressed in ileum and colon. Found in plasma. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | |||||||
| InterPro |
IPR000879
Guanylin |
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| PFAM |
PF02058
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| PRINTS |
PR00774
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| PIRSF |
PIRSF001849
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| SMART | |||||||
| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q02747 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 2980 | ||||||
| UniGene | Hs.778 | ||||||
| RefSeq | NP_291031 | ||||||
| HUGO | HGNC:4682 | ||||||
| OMIM | 139392 | ||||||
| CCDS | CCDS465 | ||||||
| HPRD | 00767 | ||||||
| IMGT | |||||||
| EMBL | AC114492 M95174 M97496 X74322 | ||||||
| GenPept | AAA35915 AAA58625 CAC22258 | ||||||