Version 5.4
Homo sapiens Protein: ADAT2
Summary
InnateDB Protein IDBP-97301.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAT2
Protein Name adenosine deaminase, tRNA-specific 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000237283
InnateDB Gene IDBG-97299 (ADAT2)
Protein Structure
UniProt Annotation
Function Probably participates in deamination of adenosine-34 to inosine in many tRNAs. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008251 tRNA-specific adenosine deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
Biological Process
GO:0002100 tRNA wobble adenosine to inosine editing
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002125 CMP/dCMP deaminase, zinc-binding
IPR016193 Cytidine deaminase-like
PFAM PF00383
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z6V5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 134637
UniGene Hs.709561
RefSeq NP_872309
HUGO HGNC:21172
OMIM 615388
CCDS CCDS43511
HPRD
IMGT
EMBL AK126201 AL031320 BC037955 BX538182 CH471051
GenPept AAH37955 BAG54295 CAD92490 CAD98054 EAW47868

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca