InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EBNA1BP2

Summary

InnateDB Protein

IDBP-97347.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EBNA1BP2

Protein Name

EBNA1 binding protein 2

Synonyms

EBP2; NOBP; P40;

Species

Homo sapiens

Ensembl Protein

ENSP00000236051

InnateDB Gene

IDBG-97345 (EBNA1BP2)

Protein Structure

UniProt Annotation

Function

Required for the processing of the 27S pre-rRNA. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:19170763, ECO:0000269PubMed:2879624}. Note=Associated with the nucleolus in an RNA-dependent manner.

Disease Associations

Tissue Specificity

Ubiquitous. {ECO:0000269PubMed:11327720}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	58 [view]
Protein-Protein	57 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0042254

ribosome biogenesis

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR008610 Eukaryotic rRNA processing

PFAM

PF05890

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99848

PhosphoSite

PhosphoSite-Q99848

TrEMBL

Q6IB29

UniProt Splice Variant

Entrez Gene

10969

UniGene

Hs.673773

RefSeq

NP_006815

HUGO

HGNC:15531

OMIM

614443

CCDS

CCDS478

HPRD

16849

IMGT

EMBL

AB451256 AB451381 AK223455 BC009175 BT006920 CH471059 CR456975 U86602

GenPept

AAB46731 AAH09175 AAP35566 BAD97175 BAG70070 BAG70195 CAG33256 EAX07112