InnateDB Protein
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IDBP-97638.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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B4GALT2
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Protein Name
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UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
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Synonyms
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B4Gal-T2; B4Gal-T3; beta4Gal-T2;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000361399
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InnateDB Gene
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IDBG-97636 (B4GALT2)
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Protein Structure
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Function |
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose.
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Subcellular Localization |
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.
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Disease Associations |
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Tissue Specificity |
Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003831
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beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
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GO:0003945
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N-acetyllactosamine synthase activity
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GO:0004461
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lactose synthase activity
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GO:0008378
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galactosyltransferase activity
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GO:0046872
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metal ion binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003859
Beta-1,4-galactosyltransferase
IPR027791
Galactosyltransferase, C-terminal
IPR029044
Nucleotide-diphospho-sugar transferases
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PFAM |
PF02709
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PRINTS |
PR02050
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O60909
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PhosphoSite |
PhosphoSite-O60909
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TrEMBL |
B3KQA5
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UniProt Splice Variant |
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Entrez Gene |
8704
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UniGene |
Hs.632403
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RefSeq |
NP_003771
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HUGO |
HGNC:925
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OMIM |
604013
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CCDS |
CCDS506
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HPRD |
04928
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IMGT |
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EMBL |
AB024434
AF038660
AK074533
AK095873
AK293418
AL137647
AL139220
AL357079
BC096821
CH471059
Y12510
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GenPept |
AAC39733
AAH96821
BAA75819
BAG51967
BAG53152
BAG56925
CAA73112
CAB70857
CAI16802
CAI16803
CAI19431
CAI19432
EAX07062
EAX07063
EAX07064
EAX07065
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