Version 5.4
Homo sapiens Protein: ERI3
Summary
InnateDB Protein IDBP-97703.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERI3
Protein Name ERI1 exoribonuclease family member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361331
InnateDB Gene IDBG-97699 (ERI3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006055 Exonuclease
IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III
PFAM PF00929
PRINTS
PIRSF
SMART SM00479
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43414
PhosphoSite PhosphoSite-O43414
TrEMBL B4DN03
UniProt Splice Variant
Entrez Gene 79033
UniGene Hs.629028
RefSeq NP_076971
HUGO HGNC:17276
OMIM 609917
CCDS CCDS30696
HPRD 15175
IMGT
EMBL AC004254 AF007157 AK290567 AK293833 AK297708 AL035417 AL390776 BC001072 BC004456 CH471059
GenPept AAC04618 AAC19158 AAH01072 AAH04456 BAF83256 BAG57236 BAG60065 CAI12491 CAI12494 CAI23194 CAI23196 EAX07044 EAX07045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca