Version 5.4
Homo sapiens Protein: TMEM53
Summary
InnateDB Protein IDBP-97747.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM53
Protein Name transmembrane protein 53
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361311
InnateDB Gene IDBG-97739 (TMEM53)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008547 Protein of unknown function DUF829, TMEM53
IPR029058 Alpha/Beta hydrolase fold
PFAM PF05705
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P2H8
PhosphoSite PhosphoSite-Q6P2H8
TrEMBL B4DI10
UniProt Splice Variant
Entrez Gene 79639
UniGene Hs.734049
RefSeq NP_078863
HUGO HGNC:26186
OMIM
CCDS CCDS511
HPRD 07989
IMGT
EMBL AK026006 AK295356 AK296548 AL122004 AL832539 BC064520 CH471059 CR457348
GenPept AAH64520 BAB15317 BAG58322 BAG59172 CAG33629 CAI22342 CAI46125 EAX07029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca