InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SYNE1

Summary

InnateDB Protein

IDBP-98033.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SYNE1

Protein Name

spectrin repeat containing, nuclear envelope 1

Synonyms

8B; ARCA1; C6orf98; CPG2; dJ45H2.2; EDMD4; MYNE1; Nesp1; SCAR8;

Species

Homo sapiens

Ensembl Protein

ENSP00000341887

InnateDB Gene

IDBG-98013 (SYNE1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.

Experimentally validated
Total	34 [view]
Protein-Protein	34 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006810	transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR010978 tRNA-binding arm
IPR011527 ABC transporter type 1, transmembrane domain
IPR012315 KASH domain
IPR018159 Spectrin/alpha-actinin
IPR022682 Peptidase C2, calpain, large subunit, domain III

PFAM

PF00307
PF00435
PF10541
PF01067

PRINTS

PIRSF

SMART

SM00033
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite