InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UQCRH

Summary

InnateDB Protein

IDBP-98110.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UQCRH

Protein Name

ubiquinol-cytochrome c reductase hinge protein

Synonyms

QCR6; UQCR8;

Species

Homo sapiens

Ensembl Protein

ENSP00000309565

InnateDB Gene

IDBG-98108 (UQCRH)

Protein Structure

UniProt Annotation

Function

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008121	ubiquinol-cytochrome-c reductase activity

Biological Process

GO:0006119	oxidative phosphorylation
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
GO:0009060	aerobic respiration
GO:0022904	respiratory electron transport chain
GO:0044237	cellular metabolic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process
GO:1902600	hydrogen ion transmembrane transport