Version 5.4
Homo sapiens Protein: MYCT1
Summary
InnateDB Protein IDBP-98121.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYCT1
Protein Name myc target 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356214
InnateDB Gene IDBG-98119 (MYCT1)
Protein Structure
UniProt Annotation
Function May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12673574}. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.
Disease Associations
Tissue Specificity Down-regulated in gastric cancer tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N699
PhosphoSite PhosphoSite-Q8N699
TrEMBL D6Q1S4
UniProt Splice Variant
Entrez Gene 80177
UniGene Hs.708579
RefSeq NP_079383
HUGO HGNC:23172
OMIM
CCDS CCDS5239
HPRD 17617
IMGT
EMBL AF527367 AK024922 AL390960 AL834500 BC022556 BC128463 BC128464 CH471051 GU997693
GenPept AAH22556 AAI28464 AAI28465 AAM88866 ADG03644 BAB15035 CAD39158 CAI23573 EAW47726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca