Version 5.4
Homo sapiens Protein: SYTL3
Summary
InnateDB Protein IDBP-98472.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYTL3
Protein Name synaptotagmin-like 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000353631
InnateDB Gene IDBG-98470 (SYTL3)
Protein Structure
UniProt Annotation
Function May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions (By similarity). {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0012505 endomembrane system
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR010911 Zinc finger, FYVE-type
IPR011011 Zinc finger, FYVE/PHD-type
PFAM PF00168
PF02318
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q4VX76
PhosphoSite PhosphoSite-Q4VX76
TrEMBL
UniProt Splice Variant
Entrez Gene 94120
UniGene
RefSeq NP_001229313
HUGO HGNC:15587
OMIM
CCDS CCDS56458
HPRD 15462
IMGT
EMBL AL589931 BC085612 BC100830 BC100831 CH471051
GenPept AAH85612 AAI00831 AAI00832 CAI95305 EAW47653

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca