Version 5.4
Homo sapiens Protein: TAGAP
Summary
InnateDB Protein IDBP-98533.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAGAP
Protein Name T-cell activation RhoGTPase activating protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000340217
InnateDB Gene IDBG-98525 (TAGAP)
Protein Structure
UniProt Annotation
Function May function as a GTPase-activating protein and may play important roles during T-cell activation. {ECO:0000269PubMed:15177553}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PRINTS
PIRSF
SMART SM00324
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N103
PhosphoSite PhosphoSite-Q8N103
TrEMBL
UniProt Splice Variant
Entrez Gene 117289
UniGene Hs.614586
RefSeq NP_620165
HUGO HGNC:15669
OMIM 609667
CCDS CCDS5263
HPRD 18143
IMGT
EMBL AF314817 AF385429 AF385430 AK097090 AL035530 BC015859 BC111731
GenPept AAH15859 AAI11732 AAL16675 AAM43830 AAM43831 BAC04947 CAI19231 CAI19232 CAI19233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca