Version 5.4
Homo sapiens Protein: C6orf120
Summary
InnateDB Protein IDBP-99231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C6orf120
Protein Name chromosome 6 open reading frame 120
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000346931
InnateDB Gene IDBG-99229 (C6orf120)
Protein Structure
UniProt Annotation
Function May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes. {ECO:0000269PubMed:22340178}.
Subcellular Localization Secreted {ECO:0000269PubMed:22340178}. Note=Secreted by hepatocytes.
Disease Associations
Tissue Specificity Mainly expressed in hepatocytes and some weak expression in germinal center cells of lymph nodes. {ECO:0000269PubMed:22340178}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z4R8
PhosphoSite PhosphoSite-Q7Z4R8
TrEMBL J3KQ97
UniProt Splice Variant
Entrez Gene 387263
UniGene Hs.708181
RefSeq NP_001025034
HUGO HGNC:21247
OMIM
CCDS CCDS34575
HPRD
IMGT
EMBL AF451991 AK295061 AL513547 BC051700 CH471051
GenPept AAH51700 AAP97690 BAG58110 CAI12315 EAW47445 EAW47446

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca