Version 5.4
Homo sapiens Protein: TCTE3
Summary
InnateDB Protein IDBP-99260.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCTE3
Protein Name t-complex-associated-testis-expressed 3
Synonyms TCTEX1D3;
Species Homo sapiens
Ensembl Protein ENSP00000355736
InnateDB Gene IDBG-99258 (TCTE3)
Protein Structure
UniProt Annotation
Function May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasmic granule {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed predominantly in testis. Also expressed in brain, lung and trachea. {ECO:0000269PubMed:11278908, ECO:0000269PubMed:12584439}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
Biological Process
GO:0006810 transport
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0016020 membrane
GO:0030286 dynein complex
Protein Structure and Domains
PDB ID
InterPro IPR005334 Tctex-1
PFAM PF03645
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IZS6
PhosphoSite PhosphoSite-Q8IZS6
TrEMBL
UniProt Splice Variant
Entrez Gene 6991
UniGene
RefSeq NP_777570
HUGO HGNC:11695
OMIM 186977
CCDS CCDS5310
HPRD 01747
IMGT
EMBL AF519569 AL354892 BC113639 CH471051
GenPept AAI13640 AAN34631 CAI19973 EAW47439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca