InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NFIA

Summary

InnateDB Protein

IDBP-99292.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NFIA

Protein Name

nuclear factor I/A

Synonyms

CTF; NF-I/A; NF1-A; NFI-A; NFI-L;

Species

Homo sapiens

Ensembl Protein

ENSP00000360231

InnateDB Gene

IDBG-99286 (NFIA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.

Experimentally validated
Total	34 [view]
Protein-Protein	33 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0006260	DNA replication
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0014070	response to organic cyclic compound
GO:0019079	viral genome replication
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000647 CTF transcription factor/nuclear factor 1
IPR003619 MAD homology 1, Dwarfin-type
IPR019548 CTF transcription factor/nuclear factor 1, N-terminal
IPR020604 CTF transcription factor/nuclear factor 1, DNA-binding domain

PFAM

PF00859
PF03165
PF10524

PRINTS

PIRSF

SMART

SM00523

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q12857