Homo sapiens Protein: ANKRD13C
Summary
InnateDB Protein IDBP-99645.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANKRD13C
Protein Name ankyrin repeat domain 13C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359982
InnateDB Gene IDBG-99643 (ANKRD13C)
Protein Structure
UniProt Annotation
Function Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER. {ECO:0000269PubMed:20959461}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:20959461}. Note=Associated with the cytosolic side.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
Biological Process
GO:0006621 protein retention in ER lumen
GO:0010869 regulation of receptor biosynthetic process
GO:2000209 regulation of anoikis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR021832 Ankyrin repeat domain-containing protein 13
PFAM PF00023
PF13606
PF11929
PF12796
PF11904
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N6S4
PhosphoSite PhosphoSite-Q8N6S4
TrEMBL
UniProt Splice Variant
Entrez Gene 81573
UniGene Hs.105016
RefSeq NP_110443
HUGO HGNC:25374
OMIM 615125
CCDS CCDS648
HPRD 13176
IMGT
EMBL AK074187 AL136717 AL158839 AL353771 AL354721 BC016937 BC028840
GenPept AAH16937 AAH28840 BAG51959 CAB66651 CAH70969 CAH70970 CAH73081 CAH73082 CAI22330 CAI22331