Version 5.4
Homo sapiens Protein: ZRANB2
Summary
InnateDB Protein IDBP-99693.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZRANB2
Protein Name zinc finger, RAN-binding domain containing 2
Synonyms ZIS; ZIS1; ZIS2; ZNF265;
Species Homo sapiens
Ensembl Protein ENSP00000359958
InnateDB Gene IDBG-99691 (ZRANB2)
Protein Structure
UniProt Annotation
Function Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'- splice site selection. {ECO:0000269PubMed:11448987}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11448987}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 76 experimentally validated interaction(s) in this database.
Experimentally validated
Total 76 [view]
Protein-Protein 75 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001876 Zinc finger, RanBP2-type
IPR017337 Uncharacterised conserved protein UCP037956, zinc finger Ran-binding
PFAM PF00641
PRINTS
PIRSF PIRSF037956
SMART SM00547
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95218
PhosphoSite PhosphoSite-O95218
TrEMBL
UniProt Splice Variant
Entrez Gene 9406
UniGene
RefSeq NP_976225
HUGO HGNC:13058
OMIM 604347
CCDS CCDS659
HPRD 09185
IMGT
EMBL AB209568 AF065391 AF065392 AK222858 AL136945 AL512443 BC039814 CH471059
GenPept AAD09746 AAD09747 AAH39814 BAD92805 BAD96578 CAB66879 CAH70058 CAH70059 EAX06433 EAX06435

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca