InnateDB Pathway Analysis enables users to determine which biological pathways are significantly over-represented
(represented more than expected by chance) in a given gene/protein list.
InnateDB incorporates pathway annotation (all pathways not just immune relevant ones) from major public databases including KEGG, Reactome, NetPath, INOH and PID and is thus one of the most comprehensive sources of pathways available.
To do a Pathway Analysis, first upload a tab-delimited text file or Excel spreadsheet (.xls files only) of gene/protein identifiers (human, mouse or cow only) and any associated quantitative data (e.g. gene expression data fold-changes and p-values) from up to 10 conditions/time-points. Please see our help page if you are unsure how to do this and to see what IDs are accepted.
Once you have a list of pathways associated with your gene/protein list - click on the red "Pathway ORA" button at the top of the page.