Homo sapiens Gene: MCOLN2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-100003.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | MCOLN2 | ||||||||||||
Gene Name | mucolipin 2 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000153898 | ||||||||||||
Encoded Proteins |
mucolipin 2
mucolipin 2
mucolipin 2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 1:84925583-84997113 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | p22.3 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Stimuli-sensing channels pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
TRP channels pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Hs.459526 Hs.591446 | ||||||||||||
RefSeq | NM_153259 XM_005270719 XM_006710552 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | CCDS30762 | ||||||||||||
HPRD | 09584 | ||||||||||||
IMGT | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||