Homo sapiens Gene: GBP6
Summary
InnateDB Gene IDBG-100185.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GBP6
Gene Name guanylate binding protein family, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183347
Encoded Proteins
guanylate binding protein family, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:89364058-89386461
Strand Forward strand
Band p22.2
Transcripts
ENST00000370456 ENSP00000359485
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006955 immune response
GO:0042742 defense response to bacterium
GO:0071346 cellular response to interferon-gamma
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Immune System pathway
Interferon gamma signaling pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.254338
RefSeq NM_198460 XM_006710393
HUGO
OMIM
CCDS CCDS723
HPRD 13572
IMGT
EMBL
GenPept
RNA Seq Atlas