InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GNAT2

Summary

InnateDB Gene

IDBG-100852.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNAT2

Gene Name

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2

Synonyms

ACHM4; GNATC

Species

Homo sapiens

Ensembl Gene

ENSG00000134183

Encoded Proteins

IDBP-100854

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2

IDBP-807287

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:109603267-109619929

Strand

Reverse strand

Band

p13.3

Transcripts

ENST00000351050	ENSP00000251337
ENST00000622865	ENSP00000482596

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0008020	G-protein coupled photoreceptor activity
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0046872	metal ion binding

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0009642	response to light intensity
GO:0046549	retinal cone cell development
GO:0050908	detection of light stimulus involved in visual perception

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0001917	photoreceptor inner segment
GO:0005834	heterotrimeric G-protein complex
GO:0005886	plasma membrane
GO:0042622	photoreceptor outer segment membrane