Version 5.4
Homo sapiens Gene: VANGL1
Summary
InnateDB Gene IDBG-101350.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VANGL1
Gene Name vang-like 1 (van gogh, Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173218
Encoded Proteins
IDBP-101352
vang-like 1 (van gogh, Drosophila)
IDBP-101354
vang-like 1 (van gogh, Drosophila)
IDBP-101356
vang-like 1 (van gogh, Drosophila)
IDBP-101358
vang-like 1 (van gogh, Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:115641953-115698224
Strand Forward strand
Band p13.1
Transcripts
ENST00000355485 ENSP00000347672
ENST00000369510 ENSP00000358523
ENST00000310260 ENSP00000310800
ENST00000369509 ENSP00000358522
ENST00000478369
ENST00000474344
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027860
View Gene Order
ENSBTAG00000005788
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04310
Wnt signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.515130 Hs.604930
RefSeq NM_001172411 NM_001172412 NM_138959 XM_006710935 XM_006710936
HUGO
OMIM
CCDS CCDS53350 CCDS883
HPRD 18279
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca