Homo sapiens Gene: TARS2
Summary
InnateDB Gene IDBG-102111.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TARS2
Gene Name threonyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143374
Encoded Proteins
threonyl-tRNA synthetase 2, mitochondrial (putative)
threonyl-tRNA synthetase 2, mitochondrial (putative)
threonyl-tRNA synthetase 2, mitochondrial (putative)
threonyl-tRNA synthetase 2, mitochondrial (putative)
threonyl-tRNA synthetase 2, mitochondrial (putative)
threonyl-tRNA synthetase 2, mitochondrial (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:150487364-150507609
Strand Forward strand
Band q21.2
Transcripts
ENST00000369064 ENSP00000358060
ENST00000369054 ENSP00000358050
ENST00000369053
ENST00000369051 ENSP00000358047
ENST00000438568 ENSP00000415002
ENST00000479372
ENST00000467982 ENSP00000475551
ENST00000466989
ENST00000480070
ENST00000463555
ENST00000460794
ENST00000462578
ENST00000483046
ENST00000606933 ENSP00000475847
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006435 threonyl-tRNA aminoacylation
GO:0008152 metabolic process
GO:0010467 gene expression
GO:0043039 tRNA aminoacylation
GO:0070159 mitochondrial threonyl-tRNA aminoacylation
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Mitochondrial tRNA aminoacylation pathway
tRNA Aminoacylation pathway
Gene Expression pathway
KEGG
Aminoacyl-tRNA biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL B4DQF3 U3KQ50
UniProt Splice Variant
Entrez Gene 80222
UniGene
RefSeq NM_001271895 NM_001271896 NM_025150
HUGO HGNC:30740
OMIM 612805
CCDS CCDS60251 CCDS60252 CCDS952
HPRD
IMGT
EMBL AK298773 AL356356
GenPept BAG60915
RNA Seq Atlas 102465529 80222