Version 5.4
Homo sapiens Gene: INSRR
Summary
InnateDB Gene IDBG-103639.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INSRR
Gene Name insulin receptor-related receptor
Synonyms IRR
Species Homo sapiens
Ensembl Gene ENSG00000027644
Encoded Proteins
IDBP-103641
insulin receptor-related receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:156840063-156859018
Strand Reverse strand
Band q23.1
Transcripts
ENST00000368195 ENSP00000357178
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043560 insulin receptor substrate binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030238 male sex determination
GO:0031532 actin cytoskeleton reorganization
GO:0046777 protein autophosphorylation
GO:0071469 cellular response to alkalinity
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005640
View Gene Order
ENSBTAG00000003054
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa05215
Prostate cancer pathway
INOH
PID NCI
Cross-References
SwissProt P14616
TrEMBL I6U4P1
UniProt Splice Variant
Entrez Gene 3645
UniGene Hs.248138 Hs.563818
RefSeq NM_014215
HUGO HGNC:6093
OMIM 147671
CCDS CCDS1160
HPRD
IMGT
EMBL AF064078 AL158169 CH471121 J05046 JQ991924
GenPept AAC17167 AAC31759 AFM93766 CAH70009 EAW52903
RNA Seq Atlas 3645

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca