Homo sapiens Gene: HOXA6
Summary
InnateDB Gene IDBG-10445.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXA6
Gene Name homeobox A6
Synonyms HOX1; HOX1.2; HOX1B;
Species Homo sapiens
Ensembl Gene ENSG00000106006
Encoded Proteins
homeobox A6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27145396-27150603
Strand Reverse strand
Band p15.2
Transcripts
ENST00000222728 ENSP00000222728
ENST00000498652
ENST00000521478
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009952 anterior/posterior pattern specification
GO:0048704 embryonic skeletal system morphogenesis
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt P31267
TrEMBL
UniProt Splice Variant
Entrez Gene 3203
UniGene Hs.676496 Hs.679517
RefSeq NM_024014
HUGO HGNC:5107
OMIM 142951
CCDS CCDS5407
HPRD 00839
IMGT
EMBL AC004080 BC069497 BC104915 BC104917 CH236948 CH471073
GenPept AAH69497 AAI04916 AAI04918 EAL24222 EAW93875
RNA Seq Atlas 3203